For those not familiar with the criteria labels used for this research. The criteria used was the 1994 CFS-Fukuda, the 2003 Canadian Consensus Criteria and the 2015 ME/CFS IOM criteria.
The only one of those worth using for research is the CCC. Which is somewhat reassuring that that the findings are valid. But it is not a research criteria. It was created for clinical use. Any followup of that research should use patients who fulfill the more effective International Consensus Criteria (ICC) from 2011.
For those not familiar with the criteria labels used for this research. The criteria used was the 1994 CFS-Fukuda, the 2003 Canadian Consensus Criteria and the 2015 ME/CFS IOM criteria.
The only one of those worth using for research is the CCC. Which is somewhat reassuring that that the findings are valid. But it is not a research criteria. It was created for clinical use. Any followup of that research should use patients who fulfill the more effective International Consensus Criteria (ICC) from 2011.
We have a great deal of research that supports the immune dysfunction as can be seen in the research lists here: https://open.substack.com/pub/colleensteckelmeiccinfo/p/myalgic-encephalomyelitis-research?utm_source=share&utm_medium=android&r=deavh